Отдел функциональной геномики
Руководитель: Сергиев Петр Владимирович
Статьи
- MA Adrianov, Bobrov M., Mamedov I., Manskikh V., Sheval EV, Rachkova AA, Shelechova AM, Eldarov CM, Averina OA, Vyssokikh MY(2025) A set of microRNAs are differentially expressed in cachexic naked mole rat colony members after chronic heavy burden under normoxia. Biochimie, >>
- Guseva Ekaterina, Averina Olga, Isaev Sergey, Pletnev Philipp, Bragina Elizaveta, Permyakov Oleg, Buev Vitaly, Priymak Anastasia, Emelianova Mariia, Pshanichnaya Lizaveta, Romanov Evgeny, Novikova Svetlana E., Petriukov Kirill, Golovina Anna, Grigorieva O(2025) Positioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts. RNA, >>
- Bruter Alexandra V., Varlamova Ekaterina A., Stavskaya Nina I., Antysheva Zoia G., Manskikh Vasily N., Tvorogova Anna V., Korshunova Diana S., Khamidullina Alvina I., Utkina Marina V., Bogdanov Viktor P., Baikova Iuliia P., Nikiforova Alyona I., Albert Eu(2025) Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice. eLife, >>
- Guseva Ekaterina A., Averina Olga A., Buev Vitaly S., Bragina Elizaveta E., Permyakov Oleg A., Priymak Anastasia V., Emelianova Mariia A., Romanov Evgeny A., Grigoryeva Olga O., Manskikh Vasily N., Pletnev Philipp I., Sergiev Petr V.(2025) Testis-specific RNA methyltransferase NSUN7 contains a re-arranged catalytic site. Biochimie, >>
- Guseva Ekaterina A., Tereshchenkov Andrey G., Kamzeeva Polina N., Myasnikov Boris P., Slushko Georgy K., Belyaev Evgeny S., Sokolskaya Sofya Y., Golubeva Julia A., Rubtsova Maria P., Sergiev Petr V., Aralov Andrey V.(2025) AMPK-specific autophagy activator based on 1,3-diaza-2-oxophenoxazine. Bioorganic Chemistry, >>
- Sergiev Petr, Averina Olga, Golubeva Julia, Vyssokikh Mikhail, Dontsova Olga(2025) Mitoregulin, a tiny protein at the crossroads of mitochondrial functioning, stress, and disease. Frontiers in Cell and Developmental Biology, >>
- Rudenko A.Yu, Mariasina S.S., Ozhiganov R.M., Sergiev P.V., Polshakov V.I.(2025) Enzymatic Reactions of S-Adenosyl-L-Methionine: Synthesis and Applications. Biochemistry (Moscow), >>
- Antonenko Yuri N., Rudenko Alexander Y., Khailova Ljudmila S., Firsov Alexander M., Kirsanov Roman S., Lyamzaev Konstantin G., Panteleeva Alisa A., Popova Lyudmila B., Mariasina Sofia S., Kotova Elena A., Polshakov Vladimir I.(2025) Cyazofamid-dessulfonamide (CCIM) is an anionic uncoupler of oxidative phosphorylation in mitochondria and a protonophore on lipid membranes. Biochemical and Biophysical Research Communications, >>
- Руденко А.Ю., Марьясина С.С., Ожиганов Р.М., Сергиев П.В., В И.Польшаков(2025) Ферментативные реакции S-аденозил-L-метионина: синтез и превращения. Успехи биологической химии, >>
- Rudenko A.Y., Mariasina S.S., Bolikhova A.K., Nikulin M.V., Ozhiganov R.M., Vasil’ev V.G., Ikhalaynen Y.A., Khandazhinskaya A.L., Khomutov M.A., Sergiev P.V., Khomutov A.R., Polshakov V.I.(2024) Organophosphorus S-adenosyl-L-methionine mimetics: synthesis, stability, and substrate properties. Frontiers in Chemistry, >>
- Bolikhova Anastasiia K., Buyan Andrey I., Mariasina Sofia S., Rudenko Alexander Y., Chekh Daria S., Mazur Alexander M., Prokhortchouk Egor B., Dontsova Olga A., Sergiev Petr V.(2024) Study of the RNA splicing kinetics via in vivo 5-ethynyl uridine labelling. RNA, >>
- Semenovich Dmitry S., Zorova Ljubava D., Abramicheva Polina A., Andrianova Nadezda V., Elchaninov Andrey V., Petrukhina Aleksandra S., Pevzner Irina B., Manskikh Vasily N., Zorov Dmitry B., Plotnikov Egor Y.(2024) Impact of Intermittent Fasting and Dietary Restriction on Redox State, Energetic Metabolism, and Liver Injury in Common Bile Duct Ligation Model. ANTIOXIDANTS, >>
- Brezgunova Anna A., Andrianova Nadezda V., Saidova Aleena A., Potashnikova Daria M., Abramicheva Polina A., Manskikh Vasily N., Mariasina Sofia S., Pevzner Irina B., Zorova Ljubava D., Manzhulo Igor V., Zorov Dmitry B., Egor Y.Plotnikov(2024) Anti-Inflammatory Effect of Synaptamide in Ischemic Acute Kidney Injury and the Role of G-Protein-Coupled Receptor 110. International Journal of Molecular Sciences, >>
- Adrianov MA, Bobrov M., Mamedov I., Manskih V., Rachkova AA, Shelekhova AM, Eldarov CM, Averina OV, Vyssokikh MYu(2024) Повышенная физическая нагрузка в условиях нормоксии вызывает идиопатическую кахексию у Heterocephalus glaber. Bulletin of RSMU, >>
- Манских В.Н.(2024) Каркасные элементы или свободный гелеобразный межклеточный матрикс как обязательное условие для построения органных структур при регенерации. Биохимия, >>
- Manskikh V.N.(2024) Organ Frame Elements or Free Intercellular Gel-Like Matrix as Necessary Conditions for Building Organ Structures during Regeneration. Biochemistry (Moscow), >>
- Guseva Ekaterina A., Kamzeeva Polina N., Sokolskaya Sofya Y., Slushko Georgy K., Belyaev Evgeny S., Myasnikov Boris P., Pavlova Julia A., Alferova Vera A., Sergiev Petr V., Aralov Andrey V.(2024) Modified (2′-deoxy)adenosines activate autophagy primarily through AMPK/ULK1-dependent pathway. Bioorganic and Medicinal Chemistry Letters, >>
- ГОЛУБЕВА Ю.А., ГУСЕВА Е.А., ДОНЦОВА О.А., СЕРГИЕВ П.В.(2024) ПРИРОДНЫЕ АКТИВАТОРЫ АУТОФАГИИ. Биохимия, >>
- ГУСЕВА Е.А., ГОЛУБЕВА Ю.А., ДОНЦОВА О.А., СЕРГИЕВ П.В.(2024) СИНТЕТИЧЕСКИЕ АКТИВАТОРЫ АУТОФАГИИ. Биохимия, >>
- Pavlova Julia A., Guseva Ekaterina A., Dontsova Olga A., Sergiev Petr V.(2024) Natural Activators of Autophagy. Biochemistry (Moscow), >>
- Guseva Ekaterina A., Pavlova Julia A., Dontsova Olga A., Sergiev Petr V.(2024) Synthetic Activators of Autophagy. Biochemistry (Moscow), >>
- Guseva Ekaterina A., Emelianova Maria A., Sidorova Vera N., Tyulpakov Anatoly N., Dontsova Olga A., Sergiev Petr V.(2024) Diversity of Molecular Functions of RNA-Binding Ubiquitin Ligases from the MKRN Protein Family. Biochemistry (Moscow), >>
- Guseva Ekaterina A., Buev Vitaly S., Mirzaeva Sabina E., Pletnev Philipp I., Dontsova Olga A., Sergiev Petr V.(2024) Structure and Composition of Spermatozoa Fibrous Sheath in Diverse Groups of Metazoa. International Journal of Molecular Sciences, >>
- Batool Zahra, Pavlova Julia A., Paranjpe Madhura N., Tereshchenkov Andrey G., Lukianov Dmitrii A., Osterman Ilya A., Bogdanov Alexey A., Sumbatyan Natalia V., Polikanov Yury S.(2024) Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. Structure, >>
- Tereshchenkov Andrey G., Khairullina Zimfira Z., Volynkina Inna A., Lukianov Dmitrii A., Nazarov Pavel A., Pavlova Julia A., Tashlitsky Vadim N., Razumova Elizaveta A., Ipatova Daria A., Timchenko Yury V., Senko Dmitry A., Efremenkova Olga V., Paleskava A(2024) Triphenylphosphonium Analogs of Short Peptide Related to Bactenecin 7 and Oncocin 112 as Antimicrobial Agents. Pharmaceutics, >>
- Gulyaev M.V., Pavlova O.S., Rudenko A.Yu, Ozhiganov R.M., Dmitriev D.S., Pistrak A.G., Ryabikov K.N., Tarasov V.P., Pirogov Yu A.(2024) Free breathing dynamic 19F MR imaging of lungs using octafluorocyclobutane at 1.5 T. Российский электронный журнал лучевой диагностики, >>
- Rybina Anna A., Glushak Roman A., Bessonova Tatiana A., Dakhnovets Artemiy I., Rudenko Alexander Yu, Ozhiganov Ratislav M., Kaznadzey Anna D., Tutukina Maria N., Gelfand Mikhail S.(2024) Phylogeny and structural modeling of the transcription factor CsqR (YihW) from Escherichia coli. Scientific reports, >>
- Yakupova E.I., Semenovich D.S., Abramicheva P.A., Zorova L.D., Pevzner I.B., Andrianova N.V., Popkov V.A., Manskikh V.N., Bocharnikov A.D., Voronina Y.A., Zorov D.B., Plotnikov E.Y.(2023) Effects of caloric restriction and ketogenic diet on renal fibrosis after ischemia/reperfusion injury. Heliyon, >>
- Averina Olga A., Permyakov Oleg A., Emelianova Mariia A., Guseva Ekaterina A., Grigoryeva Olga O., Lovat Maxim L., Egorova Anna E., Grinchenko Andrei V., Kumeiko Vadim V., Marey Maria V., Manskikh Vasily N., Dontsova Olga A., Vyssokikh Mikhail Y., Sergiev(2023) Kidney-Related Function of Mitochondrial Protein Mitoregulin. International Journal of Molecular Sciences, >>
- Averina O.A., Permyakov O.A., Emelianova M.A., Grigoryeva O.O., Lovat M.L., Egorova A.E., Grinchenko A.V., Kumeiko V.V., Marey M.V., Manskikh V.N., Dontsova O.A., Vysokikh M.Y., Sergiev P.V.(2023) Mitoregulin Contributes to Creatine Shuttling and Cardiolipin Protection in Mice Muscle. International Journal of Molecular Sciences, >>
- Brezgunova Anna A., Andrianova Nadezda V., Popkov Vasily A., Tkachev Sergey Y., Manskikh Vasily N., Pevzner Irina B., Zorova Ljubava D., Timashev Peter S., Silachev Denis N., Zorov Dmitry B., Plotnikov Egor Y.(2023) New experimental model of kidney injury: Photothrombosis-induced kidney ischemia. Biochimica et Biophysica Acta - Molecular Basis of Disease, >>
- Карягина А.С., Орлова П.А., Жулина А.В., Кривозубов М.С., Грунина Т.М., Струкова Н.В., Никитин К.Е., Манских В.Н., Сенатов Ф.С., Громов А.В.(2023) Гибридные имплантаты на основе кальций-магниевой силикатной керамики диопсида в качестве носителя рекомбинантного BMP-2 и деминерализованного костного матрикса в качестве каркаса: эктопический остеогенез при внутримышечной имплантации у мышей. Биохимия, >>
- Karyagina Anna S., Orlova Polina A., Zhulina Anna V., Krivozubov Mikhail S., Grunina Tatyana M., Strukova Natalia V., Nikitin Kirill E., Manskikh Vasily N., Senatov Fedor S., Gromov Alexander V.(2023) Hybrid Implants Based on Calcium-Magnesium Silicate Ceramic Diopside as a Carrier of Recombinant BMP-2 and Demineralized Bone Matrix as a Scaffold: Ectopic Osteogenesis in Intramuscular Implantation in Mice. Biochemistry (Moscow), >>
- Pavlova J.A., Tereshchenkov A.G., Nazarov P.A., Lukianov D.A., Skvortsov D.A., Polshakov V.I., Vasilieva B.F., Efremenkova O.V., Kaiumov M.Y., Paleskava A., Konevega A.L., Dontsova O.A., Osterman I.A., Bogdanov A.A., Sumbatyan N.V.(2023) Conjugates of Chloramphenicol Amine and Berberine as Antimicrobial Agents. Antibiotics, >>
- Rudenko Alexander Yurievich, Zubarev Andrey Alexandrovich, Ozhiganov Ratislav Maksimovich, Mariasina Sofia Semyonovna, Rodinovskaya Lyudmila Alexandrovna, Sprague Ivan Sanin, Lyssenko Konstantin Alexandrovich, Shestopalov Anatoliy Mikhailovich(2023) Novel combinatorial approach to the synthesis of dihydropyridine (quinoline) based merocyanine dyes. ARKIVOC, >>
- Kotov Vitalii Yu, Lunkov Ivan S., Buikin Petr A., Kottsov Sergey Yu, Korlyukov Alexander A., Rudenko Alexander Yu(2023) Unusual isostructural Br/I substitution effect on the crystal structure and optical properties of hybrid halobismuthates. New Journal of Chemistry, >>
- Averina Olga A., Laptev Ivan G., Emelianova Mariia A., Permyakov Oleg A., Mariasina Sofia S., Nikiforova Alyona I., Manskikh Vasily N., Grigorieva Olga O., Bolikhova Anastasia K., Kalabin Gennady A., Dontsova Olga A., Sergiev Petr V.(2022) Mitochondrial rRNA Methylation by Mettl15 Contributes to the Exercise and Learning Capability in Mice. International Journal of Molecular Sciences, >>
- Карягина А.С., Орлова П.А., Попонова М.С., Булыгина И.Н., Чоудхари Р., Жулина А.В., Грунина Т.М., Никитин К.Е., Струкова Н.В., Генералова М.С., Рязанова А.В., Ковалёва П.А., Зимина А.И., Лукинова Е.М., Плахотнюк Е.Д., Кирсанова М.А., Колесников Е.А., Заха(2022) Гибридные имплантаты на основе кальций-магниевой силикатной керамики диопсида в качестве носителя рекомбинантного BMP-2 и деминерализованного костного матрикса в качестве каркаса: динамика репаративного остеогенеза на модели краниотомии у мышей. Биохимия, >>
- Karyagina A.S., Orlova P.A., Poponova M.S., Bulygina I.N., Choudhary R., Zhulina A.V., Grunina T.M., Nikitin K.E., Strukova N.V., Generalova M.S., Ryazanova A.V., Kovalyova P.A., Zimina A.I., Lukinova E.M., Plakhotniuk E.D., Kirsanova M.A., Kolesnikov E.A(2022) Hybrid implants based on calcium-magnesium silicate ceramics diopside as a carrier of recombinant BMP-2 and demineralized bone matrix as a scaffold: dynamics of reparative osteogenesis in a mouse craniotomy model. Biochemistry (Moscow), >>
- Senatov Fedor, Zimina Anna, Chubrik Alexander, Kolesnikov Evgeniy, Permyakova Elizaveta, Voronin Andrei, Poponova Maria, Orlova Polina, Grunina Tatyana, Nikitin Kirill, Krivozubov Mikhail, Strukova Natalia, Generalova Maria, Ryazanova Anna, Manskikh Vasil(2022) Effect of recombinant BMP-2 and erythropoietin on osteogenic properties of biomimetic PLA/PCL/HA and PHB/HA scaffolds in critical-size cranial defects model. Biomaterials Advances, >>
- Андреев-Андриевский А.А., Лагерева Е.А., Панькова Н.В., Машкин М.А., Манских В.Н., Фролова О.Ю., Фадеева О.В., Телятникова Е.В.(2022) Хроническая катетеризация мочевого пузыря, но не метаболические камеры, позволяет получать точные данные о диурезе мышей. Лабораторные животные для научных исследований, >>
- Rudenko A.Yu, Mariasina S.S., Sergiev P.V., Polshakov V.I.(2022) Analogs of S-Adenosyl-L-Methionine in Studies of Methyltransferases. Molecular Biology, >>
- Руденко А.Ю., Марьясина С.С., Сергиев П.В., Польшаков В.И.(2022) Аналоги S-аденозил-L-метионина в изучении метилтрансфераз. Молекулярная биология, >>
- Balabanova S.P., Buikin P.A., Ilyukhin A.B., Rudenko A.Yu, Dorovatovskii P.V., Korlyukov A.A., Kotov V.Yu(2022) Crystal Structure and Optical Properties of New Hybrid Halobismuthates of 2,2'-Bipyridinium Derivatives. Russian Journal of Inorganic Chemistry, >>
- Andrianova Nadezda V., Buyan Marina I., Bolikhova Anastasia K., Zorov Dmitry B., Plotnikov Egor Y.(2021) Dietary Restriction for Kidney Protection: Decline in Nephroprotective Mechanisms During Aging. Frontiers in physiology, >>
- Манских В.Н.(2021) Фиксация цинк-формалином как адекватная замена ценкер-формола при гистохимическом выявлении островковых клеток поджелудочной железы. Морфология. Архив анатомии, гистологии и эмбриологии, >>
- Andreev-Andrievskiy Alexander A., Lagereva Evgeniya A., Pankova Nadezda V., Mashkin Mikhail A., Manskikh Vasily N., Frolova Olga Yu, Fadeeva Olga V., Telyatnikova Ekaterina V.(2021) Chronic bladder catheterization for precise urine collection in awake mice. Journal of Pharmacological and Toxicological Methods, >>
- Telegin G.B., Minakov A.N., Chernov A.S., Kazakov V.A., Kalabina E.A., Manskikh V.N., Asyutin D.S., Belogurov A.A.Jr, Gabibov A.G., Konovalov N.A., Spallone A.(2021) A New Precision Minimally Invasive Method of Glial Scar Simulation in the Rat Spinal Cord Using Cryoapplication. FRONTIERS IN SURGERY, >>
- Pavlova Julia A., Khairullina Zimfira Z., Tereshchenkov Andrey G., Nazarov Pavel A., Lukianov Dmitrii A., Volynkina Inna A., Skvortsov Dmitry A., Makarov Gennady I., Abad Etna, Murayama Somay Y., Kajiwara Susumu, Paleskava Alena, Konevega Andrey L., Anton(2021) Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents. Antibiotics, >>
- Chen C-W, Pavlova JA, Lukianov DA, Tereshchenkov AG, Makarov GI, Khairullina ZZ, Tashlitsky VN, Paleskava A., Konevega AL, Bogdanov AA, Osterman IA, Sumbatyan NV, Polikanov YS(2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics, >>
- Buikin P.A., Rudenko A.Yu, Ilyukhin A.B., Kotov V.Yu(2021) Synthesis and Properties of Hybrid Halobismuthates of N-Acetonylpyridinium Derivatives. Russian Journal of Inorganic Chemistry, >>
- Demyanenko I.A., Zakharova V.V., Ilyinskaya O.P., Vasilieva T.V., Fedorov A.V., Manskikh V.N., Zinovkin R.A., Pletjushkina O.Y., Chernyak B.V., Skulachev V.P., Popova E.N.(2017) Mitochondria-targeted antioxidant SkQ1 improves dermal wound healing in genetically diabetic mice. Oxidative Medicine and Cellular Longevity, >>